Chemogenomics in drug discovery :

Additional authors: Kubinyi, Hugo. | Müller, Gerhard, -- 1963-
Series: Methods and principles in medicinal chemistry ; . v. 22 Published by : Wiley-VCH, (Weinheim :) Physical details: xxiv, 463 p. : ill. (some col.) ; 25 cm. ISBN:352730987X (hbk. : alk. paper). Year: 2004
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Item type Current library Call number Status Date due Barcode
Books Books Cental Instituite of Fisheries Education
615.19 KUB (Browse shelf(Opens below)) Withdrawn 22794

Includes bibliographical references and index.

Target family-directed masterkeyes in chemogenomics / Gehard Müller -- Drug discovery from side effects / Hugo Kubinyi -- The value of chemical genetics in drug discovery / Keith Russell and William F. Michne -- Structural aspects of binding site similarity: a 3D upgrade for chemogenomics / Andreas Bergner and Judith Günther -- The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds / Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin -- Chemical kinomics / Bert M. Klebl, Henrik Daub, and György Kéri -- Structural aspects of kinases and their inhibitors / Rogier Buijsman -- A chemical genomics approach for ion channel modulators / Karl-Heinz Baringhaus and Gerhard Hessler -- Phosphodiesterase inhibitors: a chemogenomic view / Martin Hendrix and Christopher Kallus -- Proteochemometrics: a tool for modeling the molecular interaction space / Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis -- Some principles related to chemogenomics in compound library and template design for GPCRs / Thomas R. Webb -- Computational filters in lead generation: targeting drug-like chemotypes / Wolfgang Guba and Olivier Roche -- Navigation in chemical space: ligand-based design of focused compound libraries / Gisbert Schneider and Petra Schneider -- Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates / Marcus A. Koch and Herbert Waldmann -- Combinatorial chemistry in the age of chemical genomics / Reni Joseph and Prabhat Arya.

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