TY  - BOOK
AU  - Giralt,Ernest
AU  - Peczuh,Mark
AU  - Salvatella,Xavier
TI  - Protein surface recognition: approaches for the inhibition of protein-protein interactions for drug discovery 
SN  - 9780470059050 (cloth)
AV  - RS420 .P76 2011
U1  - 615.19 GIR 22
PY  - 2011///0
CY  - Chichester, West Sussex
PB  - John Wiley & Sons
KW  - Drugs
KW  - Design
KW  - Protein-protein interactions
KW  - Proteins
KW  - Inhibitors
KW  - High throughput screening (Drug development)
KW  - metabolism
KW  - Drug Discovery
KW  - methods
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Protein Binding
KW  - Surface Properties
N1  - Includes bibliographical references and index; The discovery and characterization of protein-protein interactions / C. Bertoncini, A. Higueruelo, and Xavi Salvatella -- Biophysics of protein-protein interactions / Irene Luque -- On the logic of natural product binding in protein-protein interactivity / James J. La Clair -- Interface peptide inhibitors of PPIs / Mark W. Peczuh, and Richard T. Desmond -- Inhibition of protein-protein interactions by peptide mimics / Jorge Becerril ... [et al.] -- Discovery of inhibitors of protein-protein interactions by screening chemical libraries / Carlos García-Echeverría -- High-throughput methods of chemical synthesis applied to the preparation of inhibitors of protein-protein interactions / Annaliese K. Franz, Jared T. Shaw, and Yuchen Tang -- In silico screening / F.J. Luque, and Xavier Barril -- In vitro and in vivo screening : screening by nuclear magnetic resonance / Ernest Giralt -- In vitro and in vivo screening : methods of high throughput screening / Wenjiao Song and Qing Lin -- Case study : inhibitors of the MDM2-p53 protein-protein interaction / Sanjeev Shangary, Denzil Bernard, and Shaomeng Wang -- Case study : the discovery of potent LFA-1 antagonists / Tom Gadek
ER  -