Molecular profiling :
Molecular profiling : methods and protocols /
edited by Virginia Espina, Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA.
- Second edition.
- xiii, 414 pages : illustrations ; 25 cm.
- Methods in molecular biology, 1606 1064-3745 ; Springer protocols .
- Methods in molecular biology (Clifton, N.J.) ; v. 1606. Springer protocols (Series) .
Includes bibliographical references and index.
Tumor staging and grading : a primer / Innovations in clinical trial design in the era of molecular profiling / Personalized medicine : ethical aspects / Antibody validation by Western Blotting / Scanning electron microscopy sample preparation and imaging / One-step preservation and decalcification of bony tissue for molecular profiling / Application of hydrogel nanoparticles for the capture, concentration, and preservation of low-abundance biomarkers / Using laser capture microdissection to isolate cortical laminae in nonhuman primate brain / Western blot techniques / ELISA for monitoring nerve growth factor / Reverse phase protein microarrays / Clustering and network analysis of reverse phase protein array data / PCR : identification of genetic polymorphisms / Microsatellite analysis for identification of individuals using bone from the extinct steller's sea cow (Hydrodamalis gigas) / Somatic DNA mutation analysis / Optimization of immunostaining for prospective image analysis / Fluorescence in situ hybridization of cells, chromosomes, and formalin-fixed paraffin-embedded tissues / High-resolution image stitching as a tool to assess tissue-level protein distribution and localization / Mass spectrometry-based biomarker discovery / Quantitative mass spectrometry by isotope dilution and multiple reaction monitoring (MRM) / LC-mass spectrometry for metabolomics / Metabolomic Bioinformatic Analysis / Stable isotope quantitative N-glycan analysis by liquid separation techniques and mass spectrometry / Grant writing tips for translational research / Inventions and patents : a practical tutorial / Product development and commercialization of diagnostic or life science products for scientists and researchers / Stacy M. Telloni -- Julia D. Wulfkuhle, Alexander Spira, Kirsten H. Edmiston, and Emanuel F. Petricoin III -- G. Terry Sharrer -- Michele Signore, Valeria Manganelli, and Alex Hodge -- Jenny Ngoc Tran Nguyen and Amanda M. Harbison -- Claudius Mueller, Michael G. Harpole, and Virginia Espina -- Ruben Magni and Alessandra Luchini -- Brian A. Corgiat and Claudius Mueller -- Brianna Kim -- Justin B. Davis -- Elisa Baldelli, Valerie Calvert, Alex Hodge, Amy VanMeter, Emanuel F. Petricoin III, and Mariaelena Pierobon -- Adam Byron -- Amanda M. Harbison and Jenny Ngoc Tran Nguyen -- Jeffery F. Warner, Michael G. Harpole, and Lorelei D. Crerar -- Anthony O'Grady and Robert Cummins -- Scott M. Lawrence and Yelena G. Golubeva -- Ahmad Alamri, Jun Yeb Nam, and Jan K. Blancato -- Bryan A. Millis and Matthew J. Tyska -- Weidong Zhou, Emanuel F. Petricoin III, and Caterina Longo -- Paul Russo, Brian L. Hood, Nicholas W. Bateman, and Thomas P. Conrads -- Allyson L. Dailey -- Allyson L. Dailey -- Stefan Mittermayr, Simone Albrecht, Csaba Váradi, Silvia Millán-Martín, and Jonathan Bones -- Lindsay Wescott, Michael Laskofski, Donna Senator, and Carly Curran -- Hina Mehta, Lille Tidwell, and Lance A. Liotta -- Meghan M. Alonso.
9781493969890 1493969897
2017937315
101708890 DNLM
Molecular diagnosis--Laboratory manuals.
Pathology, Molecular--Laboratory manuals.
Molecular Diagnostic Techniques--methods.
Neoplasms--therapy.
Pathology, Molecular--methods.
Tissue Array Analysis.
Molecular diagnosis.
Pathology, Molecular.
Laboratory Manuals.
Laboratory manuals.
RB43.7 / .M652 2017
616.0756 ESP
W1 / ME9616J v.1606 2017 QY 25
Includes bibliographical references and index.
Tumor staging and grading : a primer / Innovations in clinical trial design in the era of molecular profiling / Personalized medicine : ethical aspects / Antibody validation by Western Blotting / Scanning electron microscopy sample preparation and imaging / One-step preservation and decalcification of bony tissue for molecular profiling / Application of hydrogel nanoparticles for the capture, concentration, and preservation of low-abundance biomarkers / Using laser capture microdissection to isolate cortical laminae in nonhuman primate brain / Western blot techniques / ELISA for monitoring nerve growth factor / Reverse phase protein microarrays / Clustering and network analysis of reverse phase protein array data / PCR : identification of genetic polymorphisms / Microsatellite analysis for identification of individuals using bone from the extinct steller's sea cow (Hydrodamalis gigas) / Somatic DNA mutation analysis / Optimization of immunostaining for prospective image analysis / Fluorescence in situ hybridization of cells, chromosomes, and formalin-fixed paraffin-embedded tissues / High-resolution image stitching as a tool to assess tissue-level protein distribution and localization / Mass spectrometry-based biomarker discovery / Quantitative mass spectrometry by isotope dilution and multiple reaction monitoring (MRM) / LC-mass spectrometry for metabolomics / Metabolomic Bioinformatic Analysis / Stable isotope quantitative N-glycan analysis by liquid separation techniques and mass spectrometry / Grant writing tips for translational research / Inventions and patents : a practical tutorial / Product development and commercialization of diagnostic or life science products for scientists and researchers / Stacy M. Telloni -- Julia D. Wulfkuhle, Alexander Spira, Kirsten H. Edmiston, and Emanuel F. Petricoin III -- G. Terry Sharrer -- Michele Signore, Valeria Manganelli, and Alex Hodge -- Jenny Ngoc Tran Nguyen and Amanda M. Harbison -- Claudius Mueller, Michael G. Harpole, and Virginia Espina -- Ruben Magni and Alessandra Luchini -- Brian A. Corgiat and Claudius Mueller -- Brianna Kim -- Justin B. Davis -- Elisa Baldelli, Valerie Calvert, Alex Hodge, Amy VanMeter, Emanuel F. Petricoin III, and Mariaelena Pierobon -- Adam Byron -- Amanda M. Harbison and Jenny Ngoc Tran Nguyen -- Jeffery F. Warner, Michael G. Harpole, and Lorelei D. Crerar -- Anthony O'Grady and Robert Cummins -- Scott M. Lawrence and Yelena G. Golubeva -- Ahmad Alamri, Jun Yeb Nam, and Jan K. Blancato -- Bryan A. Millis and Matthew J. Tyska -- Weidong Zhou, Emanuel F. Petricoin III, and Caterina Longo -- Paul Russo, Brian L. Hood, Nicholas W. Bateman, and Thomas P. Conrads -- Allyson L. Dailey -- Allyson L. Dailey -- Stefan Mittermayr, Simone Albrecht, Csaba Váradi, Silvia Millán-Martín, and Jonathan Bones -- Lindsay Wescott, Michael Laskofski, Donna Senator, and Carly Curran -- Hina Mehta, Lille Tidwell, and Lance A. Liotta -- Meghan M. Alonso.
9781493969890 1493969897
2017937315
101708890 DNLM
Molecular diagnosis--Laboratory manuals.
Pathology, Molecular--Laboratory manuals.
Molecular Diagnostic Techniques--methods.
Neoplasms--therapy.
Pathology, Molecular--methods.
Tissue Array Analysis.
Molecular diagnosis.
Pathology, Molecular.
Laboratory Manuals.
Laboratory manuals.
RB43.7 / .M652 2017
616.0756 ESP
W1 / ME9616J v.1606 2017 QY 25