Foundations of comparative genomics /

Mushegian, Arcady R.

Foundations of comparative genomics / Arcady R. Mushegian. - Amsterdam ; Boston : Academic Press, c2007. - ix, 265 p. : ill. ; 27 cm.

Includes bibliographical references (p. 238-257) and index.

The beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology.

9780120887941 (hard cover : alk. paper) 0120887940 (hard cover : alk. paper)

2007003418

101298156 DNLM


Genomics.
Gene mapping.
Physiology, Comparative.
Genomics--methods.
Genetic Techniques.
Sequence Analysis--methods.

QH447 / .M88 2007
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